Prince had prescription opioid medication on him and in his home when he died last week, US media reported, although autopsy results have yet to indicate why the pop icon died.
The pills were found both on Prince's person and at his Paisley Park compound, CNN and other media outlets reported Thursday, citing a law enforcement official.
The prescription pills, which are used to treat pain, were discovered "at the death scene," according to the Minneapolis Star Tribune.
The drugs' role in Prince's death is under investigation, The Tribune reported, citing unnamed sources.
The Drug Enforcement Administration has been called in to help with the case, CNN said.
The authorities have said that the pop star was alone at the time of his death, and that they don't believe suicide or foul play was involved.
Investigators are examining whether an overdose of opioids led to his death, and are trying to determine how he got the pills and from whom, The Star Tribune reported, citing sources with direct knowledge of the case.
Individuals with knowledge of an emergency stop made by Prince's plane just days before the star's death said he had overdosed on an opioid at the time, according to the Star Tribune.
He was returning from Atlanta, where he performed what would be his final full-fledged concert.
Paramedics responding to the emergency gave Prince an injection of the opioid antidote Narcan, it said.
The 57-year-old music sensation, one of the most acclaimed and unique artists of his generation, was briefly hospitalized, complaining of flu-like symptoms.
The cause of his death remains unknown.
The authorities have said that at least four weeks would be needed for results of his autopsy, which was conducted before his cremation last week.
On Wednesday, a judge appointed a special administrator to oversee Prince's estate, accepting a request from the pop star's sister.
Prince died leaving no will. He had no children or living parents.
READ: Music legend Prince dead at 57
READ: Transcript of 911 call after Prince found unresponsive
READ: No signs of trauma, suicide in Prince death: Police
READ: 10 Things We Never Knew About Prince
His sister, Tyka Nelson, who sought Bremer Trust as the special administrator, was named an heir along with five of the "Purple Rain" star's living half-siblings.
Bremer Trust will be tasked with managing Prince's estate as well as determining whether there are additional heirs.
Court officials in Minneapolis scheduled a May 2 hearing at the request of relatives with a claim to Prince's estate.
The extent of the musician's fortune is unclear, with the website Celebrity Net Worth estimating he was worth $300 million.
Prince's heirs will also control his vast vaults of unreleased material, which is said to include entirely unheard albums that were shelved.
AFP
Fri Apr 29 2016
The pills were reported to be found both on Prince's person and at his Paisley Park compound. - AFP photo
Kerja ganti paip lama di Seluruh Sarawak bermula tahun ini
Sarawak akan memulakan kerja-kerja penggantian saluran paip lama sepanjang 2,740 kilometer di seluruh negeri itu bermula tahun ini.
Julaihi beri jaminan bekalan air di Sarawak pada Hari Raya mencukupi
Menteri Utiliti dan Telekomunikasi Sarawak mengingatkan orang ramai supaya elakkan pembaziran meskipun bekalan air ketika Hari Raya nanti dijamin mencukupi.
90 peratus kawasan terlibat kebakaran hutan berjaya dipadamkan
Operasi pemadaman kebakaran hutan di Kuala Baram sejak seminggu lalu berjaya dengan 90 peratus api dikawasan terjejas berjaya dipadamkan.
Pembantu bengkel diberkas, bakar mercun tengah jalan
Tindakan seorang lelaki membakar mercun di tengah jalan ketika menyertai perarakan mengiringi upacara pengebumian dekat pekan Banting di sini mengundang padah apabila diberkas polis pada Rabu.
El Nino: Al-Sultan Abdullah tinjau Sungai Pahang, titah adakan solat hajat
Sultan Pahang Al-Sultan Abdullah Riayatuddin Al-Mustafa Billah Shah berkenan meninjau Sungai Pahang yang dilaporkan surut akibat fenomena El Nino.
Hujan roket Hizbullah gegar utara Israel
Pejuang Hizbullah pada Rabu melancarkan kira-kira 30 roket dari Lubnan ke kawasan utara Israel selepas gerakan disokong Iran itu berikrar untuk 'menghukum' rejim Zionis.
Tol percuma sempena Aidilfitri 8, 9 April - Alexander
Pengguna lebuh raya membabitkan kenderaan persendirian (Kelas 1) diberi kemudahan tol percuma selama dua hari iaitu 8 dan 9 April bersempena dengan sambutan Aidilfitri tahun ini.
Penstriman haram: Jangkitan malware berisiko akibatkan kecurian, penipuan identiti pengguna
Awas dan jangan mudah terpedaya dengan sebarang akses haram yang menawarkan pelbagai filem dan siri televisyen kerana ia mungkin menyimpan perisian hasad atau malware.
Insentif cukai baharu untuk syarikat berstatus Malaysia Digital
Perbadanan Ekonomi Digital Malaysia (MDEC) akan memperkenalkan insentif cukai baharu kepada syarikat berstatus Malaysia Digital (MD) dan syarikat berstatus Koridor Raya Multimedia (MSC) sedia ada.
Gentari setuju saranan tubuh konsortium bantu pemain solar - DPMM
Gentari Sdn Bhd menyatakan persetujuannya dengan saranan untuk mewujudkan konsortium dianggotai pemain industri solar.
Do postponements cause delays in the Courts?
Cases may often be postponed or otherwise delayed for various reasons. The truth of the matter is that these delays may be necessary due to the Rule of law and due process.
Kerajaan komited 'sifar kematian berkaitan AIDS', kata Dr Subra
Kerajaan komited dalam usaha ke arah sifar kematian berkaitan AIDS, kata Menteri Kesihatan Datuk Dr S. Subramaniam.
Lady Thatcher dan Tun Mahathir: Pemimpin Gemilang-Nikesh Mehta
Pada Rabu lepas, saya berpeluang untuk bertemu dengan mantan Perdana Menteri Malaysia keempat, iaitu Y.Bhg Tun Dr Mahathir Mohamad sewaktu lawatan beliau ke kediaman Pesuruh Jaya Tinggi British.